Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762424 | 0.86 | AVPR1A (0.47) | KCNH2 | |
| SCHEMBL23696359 | 0.81 | HRH1 (0.52) | KCNH2CYP2D6CHRM1HRH1SIGMAR1 | |
| SCHEMBL17544664 | 0.77 | RAB9A (0.44) | KCNH2HRH1RAB9A | |
| SCHEMBL10446122 | 0.76 | KDM4E (0.46) | RAB9A | |
| SCHEMBL28261191 | 0.74 | KCNH2 (0.66) | KCNH2 | |
| SCHEMBL17001812 | 0.73 | HRH1 (0.37) | KCNH2HRH1 | |
| SCHEMBL17001796 | 0.72 | KCNH2 (0.34) | KCNH2CHRM1 | |
| SCHEMBL20320078 | 0.72 | CARM1 (0.39) | KCNH2 | |
| SCHEMBL9762432 | 0.72 | KCNH2 (0.49) | KCNH2CYP2D6CHRM1HRH1 | |
| SCHEMBL9761330 | 0.72 | KCNH2 (0.49) | KCNH2CYP2D6CHRM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071855-A | Antihistamines, antiallergens | DOMPE FARMACEUTICI SPA (IT) | 1991-12-10 | — | — | US | disclosed |
| EP-0397614-A2 | Pharmacologically active piperdinylimidazopyridines | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |