SCHEMBL9762552

SCHEMBL9762552

O=[N+]([O-])c1nc(N2CCOCC2)c(O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 3/20 0.44
ALDH1A1 P00352 5/20 0.44
HPGD P15428 1/20 0.42
MAPT P10636 6/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
POLB P06746 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.37
MCL1 Q07820 1/20 0.37
AKT1 P31749 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9762150 0.72 KMT2A (0.48) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL9762560 0.71 PIK3CB (0.49) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL1123936 0.68 ALDH1A1 (0.63) CYP1A2CYP2C9ALDH1A1MAPTLMNA
SCHEMBL9761085 0.68 MAPT (0.40) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL9762450 0.67 CYP1A2 (0.56) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL9760886 0.67 ALDH1A1 (0.50) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL9761404 0.66 KMT2A (0.56) CYP1A2CYP2C9ALDH1A1HPGDMAPT
SCHEMBL9761837 0.65 CYP1A2 (0.43) CYP1A2CYP2C9ALDH1A1MAPTLMNA
SCHEMBL932547 0.65 ALDH1A1 (0.52) CYP1A2CYP2C9ALDH1A1MAPTLMNA
SCHEMBL9762223 0.65 ALDH1A1 (0.46) CYP1A2CYP2C9ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026694-A Antitumor agents THE BRITISH COLUMBIA CANCER FOUNDATION (CA) 1991-06-25 US disclosed