Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760927 | 0.72 | KMT2A (0.42) | MAPTLMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL15318232 | 0.72 | CYP2C9 (0.44) | MAPTKMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL9761405 | 0.68 | MAPT (0.46) | MAPTLMNAL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL9762552 | 0.68 | CYP1A2 (0.44) | MAPTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL9761839 | 0.67 | KMT2A (0.46) | MAPTPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9761709 | 0.67 | KMT2A (0.39) | MAPTLMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3636660 | 0.65 | MAPT (0.33) | MAPTLMNAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9761185 | 0.65 | L3MBTL1 (0.40) | MAPTLMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9762559 | 0.65 | ALDH1A1 (0.49) | MAPTPKML3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9762596 | 0.64 | MAPT (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |