Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762606 | 0.73 | KMT2A (0.42) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762579 | 0.71 | KMT2A (0.46) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL2193606 | 0.71 | KMT2A (0.50) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL2196597 | 0.71 | KMT2A (0.50) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762526 | 0.69 | HPGD (0.42) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762599 | 0.68 | RIPK1 (0.45) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762434 | 0.68 | CDK2 (0.53) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9762444 | 0.67 | RIPK1 (0.39) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9761564 | 0.66 | RIPK1 (0.52) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9761232 | 0.66 | KMT2A (0.50) | KMT2AMEN1GABBR2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |