Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761557 | 0.75 | RIPK1 (0.46) | RIPK1FYNKMT2AMAPTMEN1 | |
| SCHEMBL9760928 | 0.71 | KMT2A (0.46) | RIPK1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL9762579 | 0.70 | KMT2A (0.46) | RIPK1KMT2AMAPTMEN1LMNA | |
| SCHEMBL9761163 | 0.69 | RIPK1 (0.53) | RIPK1FYNKMT2AMAPTMEN1 | |
| SCHEMBL9761766 | 0.69 | RIPK1 (0.50) | RIPK1FYNKMT2AMAPTMEN1 | |
| SCHEMBL7323015 | 0.67 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762563 | 0.66 | KMT2A (0.47) | RIPK1KMT2AMAPTMEN1LMNA | |
| SCHEMBL9762636 | 0.65 | RIPK1 (0.41) | RIPK1FYNKMT2AMAPTMEN1 | |
| SCHEMBL9761608 | 0.65 | MAPT (0.39) | RIPK1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL6270959 | 0.65 | FYN (0.52) | RIPK1FYNLMNAPIM1CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |