Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762658 | 0.76 | ALDH1A1 (0.45) | FFAR1FFAR4MMP2MMP12TSHR | |
| SCHEMBL5314931 | 0.73 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12TSHR | |
| SCHEMBL10390190 | 0.73 | CETP (0.51) | PLA2G4BTSHRCYP3A4ALDH1A1CES2 | |
| SCHEMBL1743419 | 0.72 | PLA2G4B (0.57) | PLA2G4BTSHR | |
| SCHEMBL8659917 | 0.72 | CETP (0.54) | PLA2G4BTSHRCYP3A4ALDH1A1CES2 | |
| SCHEMBL31287839 | 0.72 | CETP (0.54) | PLA2G4BTSHRCYP3A4ALDH1A1CES2 | |
| SCHEMBL10798829 | 0.72 | CETP (0.54) | PLA2G4BTSHRCYP3A4ALDH1A1CES2 | |
| SCHEMBL4073903 | 0.71 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12TSHR | |
| SCHEMBL4071200 | 0.71 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12TSHR | |
| SCHEMBL9015870 | 0.71 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |