Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 17/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650471 | 0.98 | PLA2G4B (0.59) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL8707397 | 0.98 | PLA2G4B (0.59) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL6247942 | 0.95 | PLA2G4B (0.57) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL8823910 | 0.89 | LTA4H (0.62) | PLA2G4BPLA2G4ATSHRRECQL | |
| SCHEMBL13472198 | 0.84 | KMT2A (0.57) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL7377075 | 0.83 | NR5A1 (0.62) | PLA2G4BPLA2G4A | |
| SCHEMBL9280575 | 0.83 | KMT2A (0.56) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL24095886 | 0.82 | MEN1 (0.56) | PLA2G4BMEN1ALPLALPIALPG | |
| SCHEMBL13472202 | 0.82 | KMT2A (0.51) | MEN1ALPLALPIALPGKMT2A | |
| SCHEMBL7916259 | 0.81 | PLA2G4B (0.61) | PLA2G4BPLA2G4ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835659-B2 | Polysubstituted benzofurans and medicinal applications thereof | IKERCHEM, S.L. (ES) | 2014-09-16 | — | — | US | disclosed |
| US-20130217730-A1 | POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF | IKERCHEM, S.L. (ES) | 2013-08-22 | — | — | US | disclosed |
| EP-2569292-A1 | POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF | Ikerchem, S.L. (ES) | 2013-03-20 | — | — | EP | disclosed |
| EP-2388255-A1 | Polysubstituted benzofurans and medicinal applications thereof | Ikerchem, S.L. (ES) | 2011-11-23 | — | — | EP | disclosed |
| WO-2011141458-A1 | POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF | IKERCHEM, S.L. (ES) | 2011-11-17 | — | — | WO | disclosed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217730-A1 | POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF | AGER, TFEB, FPGS | PLA2G4B 4559/4885MEN1 3958/4885ALPL 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.