Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762904 | 0.87 | IDO1 (0.36) | IDO1HRH3SIGMAR1PPARAPPARD | |
| SCHEMBL7108908 | 0.75 | IDO1 (0.52) | IDO1HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL7108904 | 0.75 | IDO1 (0.52) | IDO1HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL9762776 | 0.74 | IDO1 (0.42) | IDO1SIGMAR1MEN1KMT2ANAAA | |
| SCHEMBL810005 | 0.73 | SIGMAR1 (0.46) | IDO1SIGMAR1MAOBPAM | |
| SCHEMBL9574219 | 0.72 | TDP1 (0.41) | IDO1SIGMAR1MEN1KMT2ANAAA | |
| SCHEMBL19457521 | 0.71 | SIGMAR1 (0.44) | IDO1SIGMAR1MAOBPAM | |
| SCHEMBL810272 | 0.71 | SIGMAR1 (0.44) | IDO1SIGMAR1MAOBPAM | |
| SCHEMBL3025355 | 0.70 | SIGMAR1 (0.43) | IDO1SIGMAR1PAM | |
| SCHEMBL2064305 | 0.70 | SIGMAR1 (0.43) | IDO1SIGMAR1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |