Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108908 | 0.83 | IDO1 (0.52) | IDO1SIGMAR1MEN1KMT2APAM | |
| SCHEMBL7108904 | 0.83 | IDO1 (0.52) | IDO1SIGMAR1MEN1KMT2APAM | |
| SCHEMBL15388016 | 0.82 | IDO1 (0.53) | IDO1SIGMAR1PAMMAOBHTR2A | |
| SCHEMBL15388017 | 0.82 | IDO1 (0.53) | IDO1SIGMAR1PAMMAOBHTR2A | |
| SCHEMBL8736684 | 0.76 | SIGMAR1 (0.44) | IDO1SIGMAR1PAMMAOBHTR2A | |
| SCHEMBL9762904 | 0.75 | IDO1 (0.36) | IDO1SIGMAR1MEN1KMT2APAM | |
| SCHEMBL9762675 | 0.74 | IDO1 (0.35) | IDO1SIGMAR1MEN1KMT2APAM | |
| SCHEMBL28661525 | 0.74 | HRH3 (0.49) | IDO1SIGMAR1MEN1KMT2APAM | |
| SCHEMBL15388020 | 0.73 | SIGMAR1 (0.42) | IDO1SIGMAR1PAMMAOBHTR2A | |
| SCHEMBL15388019 | 0.73 | SIGMAR1 (0.42) | IDO1SIGMAR1PAMMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |