⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610283 | 0.71 | — | — | |
| SCHEMBL7788004 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL11215733 | 0.65 | — | — | |
| SCHEMBL2404112 | 0.65 | — | — | |
| SCHEMBL10994788 | 0.63 | — | — | |
| SCHEMBL9762733 | 0.63 | — | — | |
| SCHEMBL1636917 | 0.62 | — | — | |
| SCHEMBL796553 | 0.61 | — | — | |
| Butane SCHEMBL11329604 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL31114647 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423686-A2 | Silacyclobutanes and process for preparation | DOW CORNING CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4985565-A | Silacyclobutanes | DOW CORNING CORPORATION (US) | 1991-01-15 | — | — | US | disclosed |
| US-4965367-A | Process for preparation of silacyclobutanes | DOW CORNING CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |