Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 7/20 | 0.52 |
| ▸ | ATP1B1 | P05026 | 7/20 | 0.52 |
| ▸ | ATP1A3 | P13637 | 7/20 | 0.52 |
| ▸ | ATP1B2 | P14415 | 7/20 | 0.52 |
| ▸ | ATP1A2 | P50993 | 7/20 | 0.52 |
| ▸ | ATP1B3 | P54709 | 7/20 | 0.52 |
| ▸ | FXYD2 | P54710 | 7/20 | 0.52 |
| ▸ | ATP1A4 | Q13733 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATP12A | P54707 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190252 | 0.90 | ATP1A1 (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3119182 | 0.86 | ATP1A1 (0.48) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7279917 | 0.85 | TP53 (0.46) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11806297 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL21578272 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7309200 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7279420 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL8999665 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11654361 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL61225 | 0.84 | TP53 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003054-A | Diagnostic immunoassay for digoxin by solid phase separation | ABBOTT LABORATORIES (US) | 1991-03-26 | — | — | US | disclosed |