Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 13/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 13/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133651 | 0.84 | PARP10 (0.73) | PARP10LPAR1LPAR5 | |
| SCHEMBL28276502 | 0.83 | PARP10 (0.67) | PARP10MAPTRAB9ALPAR1LPAR5 | |
| SCHEMBL11548018 | 0.83 | MAOB (0.58) | PARP10MAPTHPGDRAB9AMAOB | |
| SCHEMBL30356696 | 0.83 | MAOB (0.58) | PARP10MAPTHPGDRAB9AMAOB | |
| SCHEMBL30289632 | 0.83 | PARP10 (1.00) | PARP10MAOBLPAR1LPAR5 | |
| SCHEMBL9762139 | 0.83 | PARP10 (0.71) | PARP10LPAR1LPAR5FAAH | |
| SCHEMBL3022362 | 0.83 | PARP10 (1.00) | PARP10MAOBLPAR1LPAR5 | |
| SCHEMBL11833021 | 0.82 | PARP10 (0.54) | PARP10MAPTLPAR1LPAR5 | |
| SCHEMBL9861909 | 0.82 | MAPT (0.64) | PARP10MAPTHPGDRAB9AMAOB | |
| SCHEMBL11305101 | 0.82 | MEN1 (0.55) | PARP10MAPTRAB9AMAOBLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116018138-A | Substituted 1H-imidazo [1,2-b ] pyrazole-3-carboxamides as inhibitors of brunauer tyrosine kinase | 河南知微生物医药有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022012550-A1 | SUBSTITUTED 1H-IMIDAZO [1, 2-B] PYRAZOLE-3-CARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2022-01-20 | — | — | WO | disclosed |
| US-5012017-A | Peroxide oxidation of halogenated phenoxyphenones to phenoxyophenyl esters, then conversions to phenoxyphenols | DOWELANCO (US) | 1991-04-30 | — | — | US | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| US-4301313-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | ELI-LILLY AND COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4226887-A | P-BIPHENYLYLACETYLENE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4136200-A | PHENYLBUTANOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4049823-A | Phenylbutanol derivatives and compositions containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-20 | — | — | US | disclosed |
| US-3991212-A | PHENYLACETYLENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3939278-A | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-02-17 | — | — | US | disclosed |