Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302271 | 0.84 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1KDM4EKCNH3 | |
| SCHEMBL9763194 | 0.84 | TAAR1 (0.56) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| Pyrimethanil SCHEMBL20817 | 0.82 | SMN1; SMN2 (0.71) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| SCHEMBL13547971 | 0.82 | RECQL (0.50) | TAAR1SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL9497419 | 0.82 | RAB9A (0.52) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| SCHEMBL9505703 | 0.81 | TAAR1 (0.54) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| SCHEMBL27261700 | 0.81 | TAAR1 (0.54) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| SCHEMBL28139778 | 0.81 | TAAR1 (0.50) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| Pyrimethanil SCHEMBL10664468 | 0.81 | SMN1; SMN2 (0.69) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A | |
| Pyrimethanil SCHEMBL22041985 | 0.81 | SMN1; SMN2 (0.69) | TAAR1SMN1; SMN2HTTSLC2A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |