Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505657 | 0.85 | RAB9A (0.48) | HTTKDM4EMAPTLMNAMEN1 | |
| SCHEMBL13547969 | 0.85 | KCNH3 (0.50) | TAAR1SMN1; SMN2KCNH3HTTVSIR | |
| SCHEMBL13547970 | 0.84 | VSIR (0.51) | SMN1; SMN2KCNH3HTTVSIRMAPT | |
| SCHEMBL9763194 | 0.81 | TAAR1 (0.56) | TAAR1SMN1; SMN2HTTKDM4EMAPT | |
| SCHEMBL9762820 | 0.81 | TAAR1 (0.56) | TAAR1SMN1; SMN2KCNH3HTTVSIR | |
| SCHEMBL9762436 | 0.81 | TAAR1 (0.47) | TAAR1SMN1; SMN2KCNH3HTTVSIR | |
| SCHEMBL9502856 | 0.80 | KCNH3 (0.46) | SMN1; SMN2KCNH3VSIRMAPTMEN1 | |
| Pyrimethanil SCHEMBL20817 | 0.80 | SMN1; SMN2 (0.71) | TAAR1SMN1; SMN2KCNH3HTTKDM4E | |
| SCHEMBL27261700 | 0.79 | TAAR1 (0.54) | TAAR1SMN1; SMN2KCNH3HTTKDM4E | |
| SCHEMBL2206867 | 0.79 | MAPT (0.43) | TAAR1SMN1; SMN2KCNH3HTTVSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295210-B1 | MICROBICIDES | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | claimed |
| EP-0295210-A1 | Microbicides | CIBA-GEIGY AG (CH) | 1988-12-14 | — | — | EP | claimed |
| US-9006243-B2 | HIV inhibiting 6-substituted pyrimidines | JANSSEN R&D IRELAND (IE) | 2015-04-14 | — | — | US | disclosed |
| US-20100016317-A1 | HIV INHIBITING 6-SUBSTITUTED PYRIMIDINES | JANSSEN SCIENCES IRELAND UC (IE) | 2010-01-21 | — | — | US | disclosed |
| EP-0295210-B1 | MICROBICIDES | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4897396-A | AGRICULTURAL INSECTICIDES, PESTICIDES AND FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0295210-A1 | Microbicides | CIBA-GEIGY AG (CH) | 1988-12-14 | — | — | EP | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016317-A1 | HIV INHIBITING 6-SUBSTITUTED PYRIMIDINES | CCR5, CTR9, NR1H3 | TAAR1 2495/4885SMN1; SMN2 4738/4885KCNH3 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.