Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762899 | 0.91 | GAA (0.48) | GAAPOLBALDH1A1LMNATSHR | |
| SCHEMBL10795123 | 0.84 | MEN1 (0.49) | GAAPOLBALDH1A1MAPTHTT | |
| SCHEMBL10798749 | 0.81 | MEN1 (0.55) | GAAPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10795158 | 0.77 | MAPT (0.62) | GAAPOLBALDH1A1MAPTHTT | |
| SCHEMBL11460570 | 0.77 | ALDH1A1 (0.48) | POLBALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9762950 | 0.77 | GAA (0.43) | GAAPOLBALDH1A1LMNATSHR | |
| SCHEMBL28892333 | 0.76 | HDAC8 (0.46) | GAAPOLBLMNAMAPTHTT | |
| SCHEMBL22791495 | 0.76 | GAA (0.58) | GAAPOLBALDH1A1LMNATSHR | |
| SCHEMBL7657031 | 0.76 | GAA (0.50) | GAAPOLBALDH1A1LMNATSHR | |
| SCHEMBL10126545 | 0.75 | GUCY1A1 (0.59) | GAAPOLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |