Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917367 | 0.92 | TSHR (0.67) | TSHRALDH1A1TDP1HSD17B10PDCD1 | |
| SCHEMBL28080657 | 0.82 | TDP1 (0.83) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL2464406 | 0.81 | TDP1 (0.74) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL43962 | 0.81 | TDP1 (0.72) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL6398395 | 0.80 | TDP1 (0.52) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL13268393 | 0.79 | LMNA (0.53) | TSHRALDH1A1TDP1HSD17B10PDCD1 | |
| Isopropylbenzene SCHEMBL25311758 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10PDCD1 | |
| Isopropylbenzene SCHEMBL2319730 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10PDCD1 | |
| SCHEMBL27467971 | 0.78 | TSHR (0.56) | TSHRALDH1A1TDP1HSD17B10PDCD1 | |
| Tert-Butyl Hydroperoxide SCHEMBL28098403 | 0.78 | TDP1 (0.69) | TSHRALDH1A1TDP1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066726-A | Addition polymers reacted with glycidyl acrylate or methacrylate, free radical catalyst | SHELL OIL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |