Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310071 | 0.73 | MAPT (0.52) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL27699296 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL27645641 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL27645537 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL10205946 | 0.69 | ALDH1A1 (0.69) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL28147295 | 0.68 | ALDH1A1 (0.78) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL12176236 | 0.66 | ALDH1A1 (0.46) | ALDH1A1MAPTPKMHTTPTGS2 | |
| SCHEMBL6672586 | 0.66 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMHTTKDM4E | |
| SCHEMBL9763027 | 0.66 | MEN1 (0.81) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL13045336 | 0.66 | CNR2 (0.40) | ALDH1A1MAPTPKMHTTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5034409-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-4694018-A | ANTIINFLAMMATORY ANTIALLERGENS | G. D. SERALE & CO. (US) | 1987-09-15 | — | — | US | disclosed |
| US-4694018-A | ANTIINFLAMMATORY ANTIALLERGENS | G. D. SERALE & CO. (US) | 1987-09-15 | — | — | US | disclosed |
| US-4694018-A | ANTIINFLAMMATORY ANTIALLERGENS | G. D. SERALE & CO. (US) | 1987-09-15 | — | — | US | disclosed |