SCHEMBL9763087

SCHEMBL9763087

NC(=O)CCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCC(N)=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
PKM P14618 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HDAC3 O15379 3/20 0.49
HDAC4 P56524 3/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC7 Q8WUI4 3/20 0.49
HDAC2 Q92769 3/20 0.49
HDAC10 Q969S8 3/20 0.49
HDAC11 Q96DB2 3/20 0.49
HDAC8 Q9BY41 3/20 0.49
HDAC6 Q9UBN7 3/20 0.49
HDAC9 Q9UKV0 3/20 0.49
HDAC5 Q9UQL6 3/20 0.49
GABBR2 O75899 1/20 0.46
GABBR1 Q9UBS5 1/20 0.46
TBXAS1 P24557 2/20 0.45
SLC6A3 Q01959 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29538601 1.00 CYP1A2 (0.53) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL27676605 0.90 CYP1A2 (0.47) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL28533624 0.87 TBXAS1 (0.58) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL7773234 0.87 TBXAS1 (0.58) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL3146207 0.87 TBXAS1 (0.58) CYP1A2CYP2D6SMN1; SMN2NPSR1HDAC3
SCHEMBL9843972 0.85 TBXAS1 (0.55) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL14360161 0.84 TBXAS1 (0.55) CYP1A2CYP2D6SMN1; SMN2NPSR1HDAC3
SCHEMBL14359790 0.83 TBXAS1 (0.54) CYP1A2CYP2D6SMN1; SMN2NPSR1HDAC3
SCHEMBL4558971 0.83 SMN1; SMN2 (0.47) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL295971 0.82 ALOX5 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9267094-B2 Drag reducing compositions and methods of manufacture and use FLOWCHEM, LTD. (US) 2016-02-23 US disclosed
US-20140360588-A1 Drag Reducing Compositions and Methods of Manufacture and Use CADENCE BANK 2014-12-11 US disclosed
US-4988463-A Antifoam agents, mono-, di-, or tri-esters with diamides and nonionic surfactants BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
US-4402702-A MINERAL OIL, BISAMIDE, NONIONIC SURFACTANT BAYER AKTIENGESELLSCHAFT (DE) 1983-09-06 US disclosed