Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763155 | 0.86 | HRH3 (0.46) | HRH3 | |
| SCHEMBL10465525 | 0.81 | KCNH2 (0.46) | TDP1L3MBTL1THRATHRBALDH1A1 | |
| SCHEMBL9763304 | 0.81 | HDAC3 (0.46) | HRH3TDP1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL10488103 | 0.80 | TDP1 (0.45) | HRH3TDP1L3MBTL1SIGMAR1THRA | |
| SCHEMBL9763048 | 0.79 | THRA (0.47) | THRATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL9574323 | 0.79 | TDP1 (0.63) | TDP1L3MBTL1SIGMAR1ALDH1A1TAAR1 | |
| SCHEMBL6679345 | 0.78 | TDP1 (0.40) | HRH3TDP1L3MBTL1THRATHRB | |
| SCHEMBL9764421 | 0.78 | THRA (0.43) | THRATHRBALDH1A1 | |
| SCHEMBL9257077 | 0.78 | TDP1 (0.53) | HRH3TDP1L3MBTL1SIGMAR1MEN1 | |
| SCHEMBL454150 | 0.78 | TDP1 (0.53) | HRH3TDP1L3MBTL1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |