Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763439 | 0.87 | THRA (0.49) | THRATHRBALDH1A1HPGDSPHK1 | |
| SCHEMBL10488145 | 0.87 | THRA (0.49) | THRATHRBALDH1A1HPGDSPHK1 | |
| SCHEMBL9764421 | 0.84 | THRA (0.43) | THRATHRBALDH1A1SPHK1 | |
| SCHEMBL1560685 | 0.80 | RARB (0.53) | THRATHRBALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL20535215 | 0.80 | ALDH1A1 (0.50) | THRATHRBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30663616 | 0.79 | ALDH1A1 (0.49) | THRATHRBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9763639 | 0.79 | RARB (0.50) | THRATHRBALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL9763088 | 0.79 | HRH3 (0.42) | THRATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL1561636 | 0.79 | THRA (0.44) | THRATHRBALDH1A1SPHK1CYP4F2 | |
| SCHEMBL9763407 | 0.78 | CYP4A11 (0.60) | THRATHRBALDH1A1HPGDSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |