Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293139 | 0.90 | APP (0.51) | APPS1PR1CYP2C19MEN1KMT2A | |
| SCHEMBL7293144 | 0.90 | APP (0.51) | APPS1PR1CYP2C19MEN1KMT2A | |
| SCHEMBL8994528 | 0.84 | S1PR1 (0.47) | APPS1PR1LMNAMEN1KMT2A | |
| SCHEMBL450847 | 0.81 | HRH3 (0.52) | APPS1PR1MEN1KMT2AS1PR3 | |
| SCHEMBL450848 | 0.81 | HRH3 (0.52) | APPS1PR1MEN1KMT2AS1PR3 | |
| SCHEMBL7284483 | 0.79 | S1PR1 (0.48) | APPS1PR1MEN1KMT2AS1PR3 | |
| SCHEMBL7284489 | 0.79 | S1PR1 (0.48) | APPS1PR1MEN1KMT2AS1PR3 | |
| SCHEMBL9873982 | 0.73 | ALDH1A1 (0.61) | KDM4ELMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9257303 | 0.73 | MEN1 (0.52) | LMNAMEN1KMT2AFKBP1ANPC1 | |
| SCHEMBL8994547 | 0.72 | ACE (0.54) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053414-A | Thiazolidine derivatives, enzyme inhibitors; amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |