Stearic Acid

Stearic Acid

SCHEMBL9763232

CC(C)(N)CO.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.68
PPARG P37231 7/20 0.68
PPARD Q03181 7/20 0.68
PPARA Q07869 7/20 0.68
HDAC11 Q96DB2 5/20 0.68
TSHR P16473 4/20 0.68
PTPN1 P18031 3/20 0.68
FABP4 P15090 3/20 0.68
ALDH1A1 P00352 2/20 0.68
TLR2 O60603 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
KMT2A Q03164 2/20 0.68
ALOX15 P16050 2/20 0.68
HSD17B10 Q99714 2/20 0.68
SLC22A6 Q4U2R8 1/20 0.68
SLC22A8 Q8TCC7 1/20 0.68
MEN1 O00255 1/20 0.68
ESR1 P03372 1/20 0.68
PDE4A P27815 1/20 0.68
PDE3A Q14432 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myristic Acid SCHEMBL11126676 1.00 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL7153676 1.00 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL246552 0.90 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL5571800 0.90 GPR84 (0.71) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL3414325 0.90 GPR84 (0.71) GPR84PPARGPPARDPPARAHDAC11
Oleic Acid SCHEMBL10582473 0.90 PPARG (0.74) PPARGPPARDPPARATSHRPTPN1
Octanoic Acid SCHEMBL3413781 0.90 GPR84 (0.77) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL31284227 0.88 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL10902881 0.88 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL19639137 0.88 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105013392-A Easily biodegraded organosilicon surfactant and preparation method thereof UNIV GUANGZHOU 2015-11-04 CN claimed
WO-2025058958-A1 pH ADJUSTER COMPRISING POLYAMINE-LACTONE/LACTIDE BASED REACTION PRODUCT(S) AND COMPOSITIONS THEREOF ISP INVESTMENTS LLC (US) 2025-03-20 WO disclosed
CN-119497729-A Surfactants comprising polyol/monol-epoxy products, methods of making, compositions, and methods of use thereof 赫尔克里士有限公司 2025-02-21 CN disclosed
EP-3390673-B1 METHOD FOR THE MANUFACTURE OF SEMI-FINISHED PRODUCTS OF LEATHER OR FUR TFL LEDERTECHNIK GMBH (DE) 2022-08-31 EP disclosed
US-10870896-B2 Solid, particulate tanning agent preparations LANXESS DEUTSCHLAND GMBH (DE) 2020-12-22 US disclosed
US-10723670-B2 Blasting compositions Dyno Nobel Asia Pacific Pty Limited (AU) 2020-07-28 US disclosed
CN-105013392-A Easily biodegraded organosilicon surfactant and preparation method thereof UNIV GUANGZHOU 2015-11-04 CN disclosed
CN-105013392-A Easily biodegraded organosilicon surfactant and preparation method thereof UNIV GUANGZHOU 2015-11-04 CN disclosed
US-20140311634-A1 BLASTING COMPOSITIONS Dyno Nobel Asia Pacific Pty Limited (AU) 2014-10-23 US disclosed
EP-2780302-A1 BLASTING COMPOSITIONS Dyno Nobel Asia Pacific Pty Limited (AU) 2014-09-24 EP disclosed
US-20140123399-A1 SOLID, PARTICULATE TANNING AGENT PREPARATIONS LANXESS DEUTSCHLAND GMBH (DE) 2014-05-08 US disclosed
WO-2013071363-A1 BLASTING COMPOSITIONS DYNO NOBEL ASIA PACIFIC PTY LTD (AU) 2013-05-23 WO disclosed
US-20120189694-A1 CO-PRECIPITATE COMPRISING A PHOSPHODIESTERASE-5 INHIBITOR (PDE-5-INHIBITOR) AND A PHARMACEUTICALLY COMPATIBLE CARRIER, PRODUCTION AND USE THEREOF RATIOPHARM GMBH (DE) 2012-07-26 US disclosed
US-5053220-A MASCARA COMPOSITION BASED ON WAXES AND KERATIN DERIVATIVES L'OREAL (FR) 1991-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120189694-A1 CO-PRECIPITATE COMPRISING A PHOSPHODIESTERASE-5 INHIBITOR (PDE-5-INHIBITOR) AND A PHARMACEUTICALLY COMPATIBLE CARRIER, PRODUCTION AND USE THEREOF PDE5A, PDE3A, PDE2A GPR84 3142/4885PPARG 2233/4885PPARD 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.