Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | FABP4 | P15090 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL11126676 | 0.90 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9763232 | 0.90 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL7153676 | 0.90 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Oleic Acid SCHEMBL22346304 | 0.90 | PPARG (0.72) | PPARGPPARDPPARATSHRPTPN1 | |
| Stearic Acid SCHEMBL28794889 | 0.89 | GPR84 (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL3413781 | 0.88 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL10902881 | 0.86 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Linoleic Acid SCHEMBL22345984 | 0.86 | PPARG (0.74) | PPARGPPARDPPARATSHRPTPN1 | |
| Dodecanoate SCHEMBL30172516 | 0.86 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9715698 | 0.86 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060193808-A1 | Composition for coating keratin fibers, comprising a fatty alcohol wax and a cellulose-based polymer | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | claimed |
| US-20060193807-A1 | Charging composition for coating keratin fibers comprising an aprotic wax | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | claimed |
| US-20050229332-A1 | Charging cosmetic makeup composition for keratin fibers | L'OREAL | 2005-10-20 | — | — | US | claimed |
| EP-4608352-A1 | AQUEOUS MAKE-UP-REMOVING COMPOSITION HAVING A MILD PEELING EFFECT | L'OREAL (FR) | 2025-09-03 | — | — | EP | disclosed |
| US-12186422-B2 | Composition for increasing silicone deposition on keratin fibers | L'OREAL (FR) | 2025-01-07 | — | — | US | disclosed |
| WO-2024088996-A1 | AQUEOUS MAKE-UP-REMOVING COMPOSITION HAVING A MILD PEELING EFFECT | L'OREAL (FR) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024003292-A1 | PRESERVING SYSTEM AND ASSOCIATED COMPOSITION | L'OREAL (FR) | 2024-01-04 | — | — | WO | disclosed |
| WO-2024003282-A1 | PRESERVING SYSTEM AND ASSOCIATED COMPOSITION | L'OREAL (FR) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023054921-A1 | COLOR COSMETIC COMPOSITION COMPRISING POLYOL-OIL EMULSION | 코스맥스 주식회사 | 2023-04-06 | — | — | WO | disclosed |
| CN-114501990-A | Seed coating composition | 玉米产品开发公司 | 2022-05-13 | — | — | CN | disclosed |
| US-20210378943-A1 | COMPOSITION FOR INCREASING SILICONE DEPOSITION ON KERATIN FIBERS | L'OREAL (FR) | 2021-12-09 | — | — | US | disclosed |
| US-20090053157-A1 | COMPOSITION COMPRISING A SOYBEAN OIL DERIVATIVE AND/OR A SALT THEREOF | L'OREAL (FR) | 2009-02-26 | — | — | US | disclosed |
| US-20090016982-A1 | COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2009-01-15 | — | — | US | disclosed |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | L'OREAL (FR) | 2008-12-04 | — | — | US | disclosed |
| US-20080124291-A1 | mascara; not only the waxes but also the pigments are homogeneously dispersed; charging make-up for the eyelashes and a satisfactory consistency compatible with producing a smooth and homogeneous deposited layer | L'OREAL (FR) | 2008-05-29 | — | — | US | disclosed |
| US-20080124292-A1 | for coating the eyelashes; at least one C16-C30 fatty acid and at least one basic amino acid,at least one glutamic acid compound and/or one of its salts, at least one sarcosine compound | L'OREAL (FR) | 2008-05-29 | — | — | US | disclosed |
| US-20070246058-A1 | Makeup and/or care kit | L'OREAL (FR) | 2007-10-25 | — | — | US | disclosed |
| US-20060193808-A1 | Composition for coating keratin fibers, comprising a fatty alcohol wax and a cellulose-based polymer | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | disclosed |
| US-20060193807-A1 | Charging composition for coating keratin fibers comprising an aprotic wax | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | disclosed |
| US-20050229332-A1 | Charging cosmetic makeup composition for keratin fibers | L'OREAL | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050229332-A1 | Charging cosmetic makeup composition for keratin fibers | KRT18, H1-10, S100A10 | GPR84 3714/4885PPARG 1712/4885PPARD 1751/4885 |
| US-20060193807-A1 | Charging composition for coating keratin fibers comprising an aprotic wax | KRT18, DSG1, CUTA | GPR84 3114/4885PPARG 1756/4885PPARD 1087/4885 |
| US-20060193808-A1 | Composition for coating keratin fibers, comprising a fatty alcohol wax and a cellulose-based polymer | KRT18, CUTA, DSG1 | GPR84 1356/4885PPARG 599/4885PPARD 812/4885 |
| US-12186422-B2 | Composition for increasing silicone deposition on keratin fibers | KRT18, TUBB6, TUBB | GPR84 2334/4885PPARG 1497/4885PPARD 661/4885 |
| US-20090053157-A1 | COMPOSITION COMPRISING A SOYBEAN OIL DERIVATIVE AND/OR A SALT THEREOF | CEL, STAT6, JAK2 | GPR84 1522/4885PPARG 846/4885PPARD 476/4885 |
| US-20210378943-A1 | COMPOSITION FOR INCREASING SILICONE DEPOSITION ON KERATIN FIBERS | KRT18, TUBB6, TUBB | GPR84 2334/4885PPARG 1497/4885PPARD 661/4885 |
| US-20080124292-A1 | for coating the eyelashes; at least one C16-C30 fatty acid and at least one basic amino acid,at least one glutamic acid compound and/or one of its salts, at least one sarcosine compound | S100A10, SGMS1, ACBD3 | GPR84 69/4885PPARG 1216/4885PPARD 2087/4885 |
| US-20090016982-A1 | COSMETIC COMPOSITION COMPRISING AN ALKYL PHOSPHATE AND A FATTY ALKYL ETHER OF POLYETHYLENE GLYCOL, PROCESSES THEREFOR AND USES THEREOF | KRT18, CUTA, PHOSPHO1 | GPR84 3710/4885PPARG 758/4885PPARD 1272/4885 |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | STS, MPST, TST | GPR84 1970/4885PPARG 404/4885PPARD 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.