Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11672412 | 0.95 | DNM1 (0.65) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL27417097 | 0.95 | DNM1 (0.73) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL28271615 | 0.93 | DNM1 (0.68) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL11344204 | 0.93 | SLC22A1 (0.68) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL2320657 | 0.93 | SLC22A1 (0.68) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Tetrahexylammonium SCHEMBL4146127 | 0.93 | SLC22A1 (0.68) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL781882 | 0.91 | DNM1 (0.60) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL6258594 | 0.91 | DNM1 (0.60) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL6259143 | 0.91 | DNM1 (0.60) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Sulfuric Acid SCHEMBL17102695 | 0.91 | SLC22A1 (0.52) | DNM1SLC22A1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021528-A | Crosslinked bisphenol containing arylcyclobutene alkyl ethers and cured compositions therefrom | SHELL OIL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4943665-A | Modified bisphenols containing arylcyclobutenealkyl ethers and cured compositions therefrom | SHELL OIL COMPANY (US) | 1990-07-24 | — | — | US | disclosed |