Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763698 | 0.86 | HRH3 (0.58) | HRH3TSHRSIGMAR1DRD2HTR2A | |
| SCHEMBL27661537 | 0.83 | HRH3 (0.65) | HRH3SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL27640973 | 0.82 | HRH3 (0.67) | HRH3SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL10488261 | 0.81 | GSK3B (0.46) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL9764494 | 0.78 | GSK3B (0.46) | SMN1; SMN2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16702209 | 0.77 | HRH3 (0.68) | HRH3SMN1; SMN2TSHRSIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL16702258 | 0.76 | HRH3 (0.67) | HRH3SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9762919 | 0.76 | HRH3 (0.46) | HRH3SIGMAR1HTR2CCHRM2ADRA2C | |
| SCHEMBL10463990 | 0.75 | HRH3 (0.48) | HRH3HPGDSIGMAR1HTR2CCHRM2 | |
| SCHEMBL10465456 | 0.74 | HRH3 (0.47) | HRH3SIGMAR1HTR2CCHRM2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |