Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488261 | 0.94 | GSK3B (0.46) | GSK3BKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10465456 | 0.82 | HRH3 (0.47) | L3MBTL3L3MBTL1 | |
| SCHEMBL9762919 | 0.81 | HRH3 (0.46) | L3MBTL3L3MBTL1 | |
| SCHEMBL9764710 | 0.80 | SLC13A5 (0.42) | KDM4EALDH1A1ALOX15HSD17B10L3MBTL3 | |
| SCHEMBL10463990 | 0.80 | HRH3 (0.48) | ALDH1A1ALOX15HPGDL3MBTL3MAPT | |
| SCHEMBL1681747 | 0.80 | GSK3B (0.53) | GSK3BKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9763380 | 0.78 | HRH3 (0.50) | KDM4EHPGDRAB9ANPC1MEN1 | |
| SCHEMBL9764418 | 0.77 | SLC13A5 (0.47) | KDM4EALDH1A1SLC13A5MAPTRAB9A | |
| SCHEMBL27279231 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1ALOX15HSD17B10L3MBTL3 | |
| SCHEMBL9764527 | 0.76 | SIGMAR1 (0.48) | MAPTRAB9ANPC1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0181709-B1 | DICHLOROANILINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | disclosed |