Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764494 | 0.94 | GSK3B (0.46) | GSK3BALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL10465456 | 0.85 | HRH3 (0.47) | L3MBTL3L3MBTL1SIGMAR1FFAR4 | |
| SCHEMBL9762919 | 0.84 | HRH3 (0.46) | L3MBTL3L3MBTL1SIGMAR1FFAR4 | |
| SCHEMBL10463990 | 0.83 | HRH3 (0.48) | ALDH1A1ALOX15HPGDL3MBTL3MAPT | |
| SCHEMBL27279231 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EALOX15HSD17B10L3MBTL3 | |
| SCHEMBL9763380 | 0.81 | HRH3 (0.50) | KDM4EHPGDRAB9ANPC1MEN1 | |
| SCHEMBL10488181 | 0.80 | SLC13A5 (0.42) | ALDH1A1KDM4EALOX15HSD17B10L3MBTL3 | |
| SCHEMBL1681747 | 0.80 | GSK3B (0.53) | GSK3BALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL10488193 | 0.76 | SLC13A5 (0.52) | ALDH1A1KDM4ESLC13A5MAPTRAB9A | |
| SCHEMBL1532698 | 0.75 | SLC13A5 (0.49) | GSK3BALDH1A1KDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |