Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.50 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TTK | P33981 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300191 | 0.76 | CHEK1 (0.48) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL2945140 | 0.76 | CHEK1 (0.48) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL31357524 | 0.75 | MAP2K4 (0.60) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL5822772 | 0.75 | MAP2K4 (0.60) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL9297750 | 0.75 | NFKB1 (0.67) | KDM4EGAANFKB1CA1CA2 | |
| SCHEMBL17583974 | 0.71 | MAP2K4 (0.51) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL8641080 | 0.71 | NFKB1 (0.72) | KDM4EGAAMAPK1NFKB1CA1 | |
| SCHEMBL9876317 | 0.71 | IDO1 (0.58) | AURKAMAP2K4ALDH1A1KDM4EHPGD | |
| SCHEMBL2433472 | 0.70 | PTGER3 (0.66) | ALDH1A1KDM4EHPGDGAANFKB1 | |
| SCHEMBL181054 | 0.70 | PTGER3 (0.66) | ALDH1A1KDM4EHPGDGAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2229170-A | — | — | None | — | — | JP | disclosed |
| US-4990174-A | N-phenyltetrahydroindazole derivatives herbicidal compositions and use | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| JP-H02229170-A | N-PHENYLTETRAHYDROINDAZOLE DERIVATIVE AND HERBICIDE CONTAINING THE SAME | BASF AG | 1990-09-11 | — | — | JP | disclosed |