Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966393 | 1.00 | THRB (0.35) | THRBALDH1A1ALOX15 | |
| Ethylene Glycol SCHEMBL29006093 | 0.78 | OR51E2 (0.39) | — | |
| SCHEMBL9250461 | 0.78 | CHRM1 (0.36) | — | |
| SCHEMBL6434332 | 0.77 | — | — | |
| SCHEMBL2328444 | 0.77 | — | — | |
| SCHEMBL444373 | 0.77 | — | — | |
| SCHEMBL132643 | 0.77 | — | — | |
| SCHEMBL9763862 | 0.76 | — | — | |
| SCHEMBL9763853 | 0.76 | — | — | |
| SCHEMBL11501511 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036071-A | Herper virus | MEDIVIR AB (SE) | 1991-07-30 | — | — | US | disclosed |
| EP-0186640-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0186640-A1 | Derivatives of purine, process for their preparation and a pharmaceutical preparation | Medivir Aktiebolag (SE) | 1986-07-02 | — | — | EP | disclosed |