SCHEMBL444373

SCHEMBL444373

CC(C)=C(O)[C@H](O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132643 1.00
SCHEMBL2328444 1.00
Ethylene Glycol SCHEMBL29006093 0.94 OR51E2 (0.39)
Acetic Acid SCHEMBL3888013 0.92 OR51E2 (0.50)
Phosphoric Acid SCHEMBL8540518 0.87 OR51E2 (0.40)
Dimethyl Sulfoxide SCHEMBL9985876 0.87 OR51E2 (0.35)
Butyl Alcohol SCHEMBL6233982 0.83 ALDH1A1 (0.48)
Methacrylic Acid SCHEMBL10932249 0.83 OR51E2 (0.42)
Acrylic Acid SCHEMBL4814346 0.82 LMNA (0.42)
SCHEMBL1331108 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120737119-A Preparation method of L-alpha-phosphorylcholine azole 拓新药业集团股份有限公司 2025-10-03 CN disclosed
US-20250084116-A1 MIXTURE OF STEREOISOMERS OF A SULFATED GLYCOLIPID NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2025-03-13 US disclosed
EP-4460328-A1 MIXTURE OF STEREOISOMERS OF A SULFATED GLYCOLIPID NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2024-11-13 EP disclosed
US-10266565-B2 Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2019-04-23 US disclosed
US-9175038-B2 Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2015-11-03 US disclosed
US-20140142044-A1 PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE The United States of America, as represented by the Secretary, Department of Health & Human Servic (US) 2014-05-22 US disclosed
US-20120065146-A1 PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) 2012-03-15 US disclosed
EP-1838283-B1 LIPID-BASED DRUG DELIVERY SYSTEMS CONTAINING UNNATURAL PHOSPHOLIPASE A2 DEGRADABLE LIPID DERIVATIVES AND THE THERAPEUTIC USES THEREOF LIPLASOME PHARMA AS (DK) 2008-12-31 EP disclosed
US-20080014253-A1 Lipid-Based Drug Delivery Systems Containing Unnatural Phospholipase A2 Degradable Lipid Derivatives and the Therapeutic Uses Thereof LIPLASOME PHARMA A/S (DK) 2008-01-17 US disclosed
EP-1838283-A2 LIPID-BASED DRUG DELIVERY SYSTEMS CONTAINING UNNATURAL PHOSPHOLIPASE A2 DEGRADABLE LIPID DERIVATIVES AND THE THERAPEUTIC USES THEREOF Liplasome Pharma A/S (DK) 2007-10-03 EP disclosed
US-6829540-B1 Data processing, drug screening using immobilized artificial membrane chromatographic substrates in high pressure liquid chromatographic systems using aqueous mobile phases PURDUE RESEARCH FOUNDATION 2004-12-07 US disclosed
WO-2004092188-A2 ANALOGS OF LYSOPHOSPHATIDIC ACID AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2004-10-28 WO disclosed
EP-0634408-B1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO (JP) 2002-01-02 EP disclosed
EP-1015623-A1 DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES PURDUE RESEARCH FOUNDATION (US) 2000-07-05 EP disclosed
WO-1999010522-A1 DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES PURDUE RESEARCH FOUNDATION (US) 1999-03-04 WO disclosed
CN-1039331-C Depsispeptide derivative, preparation and application of same FUJISAMA PHARMACEUTICAL CO LTD (JP) 1998-07-29 CN disclosed
US-5514773-A PARASITICIDES, ANTHELMINTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-07 US disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed
CN-1080932-A Depsipeptide derivative and manufacture method thereof and purposes FUJISAWA PHARMACEUTICAL CO (JP) 1994-01-19 CN disclosed
WO-1993001196-A1 KETOALKYLGLYCEROPHOSPHOLIPIDS HAVING ANTITUMOR AND ANTI-PLATELET AGGREGATION ACTIVITIES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM LABORATORIOS MENARINI S.A. (ES) 1993-01-21 WO disclosed