Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763884 | 1.00 | TACR1 (0.43) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9763498 | 0.84 | LMNA (0.46) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9763860 | 0.81 | TACR1 (0.47) | TACR1LMNAKMT2ASMN1; SMN2PADI4 | |
| SCHEMBL9763854 | 0.81 | TACR1 (0.47) | TACR1LMNAKMT2ASMN1; SMN2PADI4 | |
| SCHEMBL9764294 | 0.80 | TACR1 (0.44) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9764285 | 0.80 | TACR1 (0.44) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9763435 | 0.79 | TACR1 (0.43) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9763438 | 0.79 | TACR1 (0.43) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL1376897 | 0.74 | KMT2A (0.51) | TACR1LMNAKMT2ASMN1; SMN2BRD4 | |
| SCHEMBL9763460 | 0.72 | CYP2C9 (0.46) | TACR1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | disclosed |