Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763854 | 1.00 | TACR1 (0.47) | TACR1ALOX5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9763435 | 0.89 | TACR1 (0.43) | TACR1LMNAKMT2ASMN1; SMN2PADI4 | |
| SCHEMBL9763438 | 0.89 | TACR1 (0.43) | TACR1LMNAKMT2ASMN1; SMN2PADI4 | |
| SCHEMBL9764294 | 0.82 | TACR1 (0.44) | TACR1LMNAKMT2ASMN1; SMN2MAPK8 | |
| SCHEMBL9764285 | 0.82 | TACR1 (0.44) | TACR1LMNAKMT2ASMN1; SMN2MAPK8 | |
| SCHEMBL9763878 | 0.81 | TACR1 (0.43) | TACR1ALOX5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9763884 | 0.81 | TACR1 (0.43) | TACR1ALOX5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9763498 | 0.80 | LMNA (0.46) | TACR1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8905162 | 0.77 | LMNA (0.46) | TACR1LMNAKMT2ASMN1; SMN2PADI4 | |
| SCHEMBL8662656 | 0.77 | LMNA (0.46) | TACR1LMNAKMT2ASMN1; SMN2PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | disclosed |