Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH4 | P08319 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684054 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL354924 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL28621809 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL3726879 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL1021842 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL5683929 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL29242009 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL3742493 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL3726882 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A | |
| SCHEMBL3739044 | 1.00 | ACE2 (0.54) | ACE2OPRM1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023223888-A1 | METHOD FOR PRODUCING POLYCARBONATE RESIN, AND ALICYCLIC POLYCARBONATE RESIN | 旭化成株式会社 | 2023-11-23 | — | — | WO | disclosed |
| CN-109721723-B | Surfactant, method for producing the same, and solution containing the same | 中日合成化学股份有限公司 | 2021-07-06 | — | — | CN | disclosed |
| EP-2132167-B1 | METHOD FOR THE PRODUCTION OF beta-KETONITRILES | BASF SE (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-8501748-B2 | Method for the production of β-ketonitriles | BASF SE (DE) | 2013-08-06 | — | — | US | disclosed |
| US-20130005970-A1 | Method for the production of beta-ketonitriles | BASF SE (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8309751-B2 | Method for the production of β-ketonitriles | BASF SE (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20110001221-A1 | DIELECTRIC LAYER | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-01-06 | — | — | US | disclosed |
| US-7829137-B2 | Fabricating dielectric layer | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-11-09 | — | — | US | disclosed |
| US-20100279963-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE, LLC (US) | 2010-11-04 | — | — | US | disclosed |
| US-7799954-B2 | Dicarbonyl derivatives and methods of use | ABRAXIS BIOSCIENCE, LLC (US) | 2010-09-21 | — | — | US | disclosed |
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0591699-A1 | N-hydroxy-N-phenylcarboxamides, processes for their production and agents containing them for the controlling of harmful fungi | BASF Aktiengesellschaft (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0589301-A1 | Carboxynilides derivatives, process for their preparation and fungicidal compositions containing them | BASF Aktiengesellschaft (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0589313-A1 | Cyclohex(en)ylcarboxamides, process for their preparation and anti-fungal agents containing them | BASF Aktiengesellschaft (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5192766-A | Platelet activating factor antagonist | SANKYO COMPANY, LIMITED (JP) | 1993-03-09 | — | — | US | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0395446-A2 | N-acryloylpiperazine derivatives, their preparation and their use as paf antagonists | Sankyo Company Limited (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4818429-A | FERROELECTRIC LIQUID CRYSTAL DISPLAY ELEMENTS; GOOD RESPONSE | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0260153-A2 | Cyclohexylphenylpyridazines | Chisso Corporation (JP) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005970-A1 | Method for the production of beta-ketonitriles | AKR1C3, AKR1C4, AKR1C1 | ACE2 1552/4885OPRM1 3316/4885ADH1B 723/4885 |
| US-20100279963-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | AADAC, DCK, MLYCD | ACE2 3329/4885OPRM1 4442/4885ADH1B 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.