SCHEMBL9763975

SCHEMBL9763975

NCCCCCCCCCCC(=O)c1cccnc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.68
HDAC8 Q9BY41 2/20 0.68
CYP3A4 P08684 1/20 0.56
PLOD2 O00469 2/20 0.54
F7 P08709 1/20 0.51
F3 P13726 1/20 0.51
SARM1 Q6SZW1 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.51
SIRT6 Q8N6T7 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
SIRT3 Q9NTG7 1/20 0.51
SIRT5 Q9NXA8 1/20 0.51
SIRT4 Q9Y6E7 1/20 0.51
HRH1 P35367 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PLOD3 O60568 1/20 0.49
PLOD1 Q02809 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010434 0.98 HDAC1 (0.66) HDAC1HDAC8CYP3A4PLOD2F7
Hydrochloric Acid SCHEMBL2259124 0.97 HDAC1 (0.64) HDAC1HDAC8CYP3A4PLOD2F7
Hydrochloric Acid SCHEMBL2259119 0.97 HDAC1 (0.64) HDAC1HDAC8CYP3A4PLOD2F7
SCHEMBL17700981 0.93 HDAC1 (0.63) HDAC1HDAC8CYP3A4PLOD2F7
SCHEMBL29963697 0.93 HDAC1 (0.63) HDAC1HDAC8CYP3A4PLOD2F7
Hydrochloric Acid SCHEMBL9490379 0.92 HDAC1 (0.61) HDAC1HDAC8CYP3A4PLOD2F7
Hydrochloric Acid SCHEMBL31026319 0.92 HDAC1 (0.61) HDAC1HDAC8CYP3A4PLOD2F7
SCHEMBL21133737 0.88 PLOD2 (0.62) HDAC1HDAC8PLOD2F7F3
SCHEMBL3380708 0.85 HDAC1 (0.70) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL9549825 0.85 HDAC1 (0.70) HDAC1HDAC8PLOD2L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994462-A N,N-Bis(nipecotyl)piperazines RESEARCH CORPORATION (US) 1991-02-19 US disclosed
US-4798830-A TETRAHYDROQUINOLINE DERIVATIVES RESEARCH CORPORATION (US) 1989-01-17 US disclosed
US-4634709-A PIPERIDINE DERIVATIVES RESEARCH CORPORATION (US) 1987-01-06 US disclosed
US-4443450-A N,N*-BIS(NIPECOTYL) PIPERAZINE RESEARCH CORPORATION (US) 1984-04-17 US disclosed