Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 5/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764047 | 1.00 | NFE2L2 (0.40) | NFE2L2CHRM3CHRM2CHRM1DHODH | |
| SCHEMBL9763895 | 0.91 | NFE2L2 (0.41) | NFE2L2CHRM3CHRM2CHRM1DHODH | |
| SCHEMBL9763900 | 0.91 | NFE2L2 (0.41) | NFE2L2CHRM3CHRM2CHRM1DHODH | |
| SCHEMBL9763859 | 0.89 | NFE2L2 (0.40) | NFE2L2CHRM3CHRM2CHRM1DHODH | |
| SCHEMBL9763855 | 0.89 | NFE2L2 (0.40) | NFE2L2CHRM3CHRM2CHRM1DHODH | |
| SCHEMBL9764278 | 0.88 | NFE2L2 (0.41) | NFE2L2CHRM3CHRM2CHRM1KEAP1 | |
| SCHEMBL9764275 | 0.88 | NFE2L2 (0.41) | NFE2L2CHRM3CHRM2CHRM1KEAP1 | |
| SCHEMBL9764355 | 0.87 | NFE2L2 (0.40) | NFE2L2KEAP1FFAR4 | |
| SCHEMBL9764351 | 0.87 | NFE2L2 (0.40) | NFE2L2KEAP1FFAR4 | |
| SCHEMBL9763570 | 0.87 | NFE2L2 (0.40) | NFE2L2KEAP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |