Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764129 | 1.00 | NOS3 (0.33) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9763573 | 0.98 | NOS3 (0.32) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9763571 | 0.98 | NOS3 (0.32) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9763568 | 0.98 | NOS3 (0.32) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL18503351 | 0.95 | NOS3 (0.31) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL12895669 | 0.95 | NOS3 (0.31) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL17547996 | 0.88 | SLC6A2 (0.34) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9763923 | 0.86 | MAOB (0.35) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9763928 | 0.86 | MAOB (0.35) | NOS3NOS1NOS2MAOBMAOA | |
| SCHEMBL9764462 | 0.86 | RIPK1 (0.33) | NOS3NOS1NOS2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553522-B2 | LC-mixtures with low frequency dependence for TFT-displays | MERCK PATENT GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |