SCHEMBL354995

SCHEMBL354995

CC1=CCCCCCCCCCCCCC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 2/20 0.38
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 3/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.32
ALOX15 P16050 1/20 0.32
CYP2A6 P11509 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
GLI1 P08151 1/20 0.31
CYP3A4 P08684 1/20 0.31
GLI2 P10070 1/20 0.31
TYMP P19971 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL354993 1.00 GSTP1 (0.38) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL6244920 1.00 GSTP1 (0.38) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL18198950 1.00 GSTP1 (0.38) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL6244923 1.00 GSTP1 (0.38) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL6244929 1.00 GSTP1 (0.38) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL11248818 0.98
SCHEMBL745837 0.90
SCHEMBL2921936 0.85 GSTP1 (0.35) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL2921942 0.85 GSTP1 (0.35) GSTP1HIF1AALDH1A1HDAC4HDAC2
SCHEMBL2921937 0.85 GSTP1 (0.35) GSTP1HIF1AALDH1A1HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504693-A1 FRAGRANCE AND FLAVOR MATERIALS Takasago International Corporation (JP) 2025-02-12 EP disclosed
WO-2023196616-A1 FRAGRANCE AND FLAVOR MATERIALS TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2023-10-12 WO disclosed
CN-114364773-A Aromatic oil mixture 西姆莱斯股份公司 2022-04-15 CN disclosed
WO-2020067079-A1 METHOD FOR PRODUCING 3-METHYLCYCLOALKENONE COMPOUND 高砂香料工業株式会社 2020-04-02 WO disclosed
US-20180297922-A1 NOVEL OCTAHYDROINDENYL PROPANAL COMPOUNDS INT FLAVORS & FRAGRANCES INC (US) 2018-10-18 US disclosed
EP-1687068-B1 SPIROEPOXY-MACROCYCLE AS PERFUMING INGREDIENT FIRMENICH & CIE (CH) 2016-03-09 EP disclosed
US-20120015009-A9 Multi-phased personal care composition comprising a blooming perfume composition THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
EP-1529770-B1 Aldehyde as perfuming or flavoring ingredient FIRMENICH & CIE (CH) 2011-08-17 EP disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. 2009-03-12 US disclosed
WO-2008134712-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. (US) 2008-11-06 WO disclosed
WO-2008070368-A2 METHODS AND COMPOSITIONS FOR SKIN CARE LIVING PROOF, INC. (US) 2008-06-12 WO disclosed
US-20070280976-A1 Multi-phased personal care composition comprising a blooming perfume composition THE PROCTER & GAMBLE COMPANY 2007-12-06 US disclosed
US-7115552-B2 Spiroepoxy-macrocycle as perfuming ingredient FIRMENICH SA (CH) 2006-10-03 US disclosed
EP-1687068-A1 SPIROEPOXY-MACROCYCLE AS PERFUMING INGREDIENT FIRMENICH SA (CH) 2006-08-09 EP disclosed
US-20060148673-A1 Spiroepoxy-macrocycle as perfuming ingredient FIRMENICH SA (CH) 2006-07-06 US disclosed
US-6933265-B2 Aldehyde as perfuming or flavoring ingredient FIRMENICH SA (CH) 2005-08-23 US disclosed
US-20050101498-A1 ALDEHYDE AS PERFUMING OR FLAVORING INGREDIENT FIRMENICH SA (CH) 2005-05-12 US disclosed
WO-2005039521-A1 SPIROEPOXY-MACROCYCLE AS PERFUMING INGREDIENT FIRMENICH SA (CH) 2005-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE MMP1, MMP9, MMP17 GSTP1 4663/4885HIF1A 308/4885ALDH1A1 2338/4885
US-20180297922-A1 NOVEL OCTAHYDROINDENYL PROPANAL COMPOUNDS OR51E2, CUTA, POLR1C GSTP1 3848/4885HIF1A 3206/4885ALDH1A1 152/4885
US-20050101498-A1 ALDEHYDE AS PERFUMING OR FLAVORING INGREDIENT ALDH1A1, ALDH5A1, ALDH18A1 GSTP1 2894/4885HIF1A 289/4885ALDH1A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.