SCHEMBL9764336

SCHEMBL9764336

Nc1cc(/N=c2\sc(=O)n3n2CCCC3)ccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPOX P50336 1/20 0.33
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9764340 1.00 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9764684 0.84 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1HPGDHSD17B10TSHR
SCHEMBL9764683 0.84 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1HPGDHSD17B10TSHR
SCHEMBL9764378 0.80 NPC1 (0.40) SMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL9764383 0.80 NPC1 (0.40) SMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL9764449 0.78 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9414261 0.76 TDP1 (0.34) SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9371520 0.74 MAPT (0.38) ALDH1A1
SCHEMBL9371523 0.74 MAPT (0.38) ALDH1A1
SCHEMBL9824588 0.73 KMT2A (0.38) SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE33745-E Thiadiazabicyclononane derivatives, processes for their production and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-11-19 US disclosed
US-4816063-A PLANT GROWTH REGULATORS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-03-28 US disclosed
EP-0238711-A1 Thiadiazabicyclononane derivatives, processes for their production and herbizidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-30 EP disclosed