Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.35 |
| ▸ | PDE1A | P54750 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764383 | 1.00 | NPC1 (0.40) | NPC1RAB9APDE7APDE1APDE1B | |
| SCHEMBL9371523 | 0.84 | MAPT (0.38) | NPC1PDE7APDE4DMEN1KMT2A | |
| SCHEMBL9371520 | 0.84 | MAPT (0.38) | NPC1PDE7APDE4DMEN1KMT2A | |
| SCHEMBL9764405 | 0.81 | NPC1 (0.40) | NPC1RAB9APDE7APDE1APDE1B | |
| SCHEMBL9764402 | 0.81 | NPC1 (0.40) | NPC1RAB9APDE7APDE1APDE1B | |
| SCHEMBL9764683 | 0.80 | SMN1; SMN2 (0.34) | PDE7APDE1APDE1BPDE1CPDE4D | |
| SCHEMBL9764336 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL9764340 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL9764449 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9764409 | 0.73 | USP2 (0.33) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33745-E | Thiadiazabicyclononane derivatives, processes for their production and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| US-4816063-A | PLANT GROWTH REGULATORS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |