Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764684 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HSP90AA1PDE5APDE1APDE1B | |
| SCHEMBL9764336 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL9764340 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL9764378 | 0.80 | NPC1 (0.40) | SMN1; SMN2HSP90AA1PDE5APDE1APDE1B | |
| SCHEMBL9764383 | 0.80 | NPC1 (0.40) | SMN1; SMN2HSP90AA1PDE5APDE1APDE1B | |
| SCHEMBL9764449 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1TSHRHSD17B10POLB | |
| SCHEMBL9414261 | 0.78 | TDP1 (0.34) | SMN1; SMN2ALDH1A1HSD17B10TDP1THRB | |
| SCHEMBL9764409 | 0.77 | USP2 (0.33) | HPGD | |
| SCHEMBL9764406 | 0.77 | USP2 (0.33) | HPGD | |
| SCHEMBL9824583 | 0.75 | KMT2A (0.38) | SMN1; SMN2ALDH1A1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33745-E | Thiadiazabicyclononane derivatives, processes for their production and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0238711-B1 | THIADIAZABICYCLONONANE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND HERBIZIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |
| US-4816063-A | PLANT GROWTH REGULATORS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |