Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19001343 | 0.85 | THRB (0.48) | THRBTDP1MAPTPOLBADRB2 | |
| SCHEMBL18172021 | 0.85 | THRB (0.44) | THRBTDP1MAPTPOLBADRB2 | |
| SCHEMBL16146892 | 0.85 | THRB (0.44) | THRBTDP1MAPTPOLBADRB2 | |
| Hydrochloric Acid SCHEMBL18172006 | 0.83 | THRB (0.43) | THRBTDP1MAPTPOLBADRB2 | |
| SCHEMBL2974587 | 0.83 | MAPT (0.56) | TDP1MAPTADRB2HTTLMNA | |
| SCHEMBL18997831 | 0.80 | TDP1 (0.44) | THRBTDP1MAPTPOLBADRB2 | |
| SCHEMBL10871089 | 0.80 | CYP1A2 (0.58) | MAPTPOLBHTTMEN1KMT2A | |
| SCHEMBL9367834 | 0.78 | THRB (0.46) | THRBTDP1MAPTPOLBHTT | |
| SCHEMBL4535349 | 0.78 | TDP1 (0.51) | THRBTDP1MAPTPOLBADRB2 | |
| SCHEMBL5349206 | 0.77 | L3MBTL1 (0.61) | TDP1MAPTPOLBADRB2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987258-A | Intermediates for disazo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0196574-B1 | 4,4'-DIAMINODIPHENYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0196574-A2 | 4,4'-Diaminodiphenyl compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-08 | — | — | EP | disclosed |