Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 18/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982300 | 0.85 | ADRB2 (0.67) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL10417732 | 0.83 | SLC2A1 (0.62) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764465 | 0.83 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764490 | 0.83 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL10467798 | 0.83 | SLC2A1 (0.53) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9764474 | 0.82 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL9021318 | 0.82 | ADRB2 (0.61) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL9509569 | 0.82 | SLC2A1 (0.52) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL10417912 | 0.81 | SLC2A1 (0.50) | SLC2A1ADRB2ADRB1SLC6A2HTR2A | |
| SCHEMBL10417908 | 0.81 | SLC2A1 (0.55) | SLC2A1ADRB2ADRB1SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181709-B1 | DICHLOROANILINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | claimed |
| EP-0181709-A1 | Dichloroaniline Derivatives | GLAXO GROUP LIMITED (GB) | 1986-05-21 | — | — | EP | claimed |
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0181709-A1 | Dichloroaniline Derivatives | GLAXO GROUP LIMITED (GB) | 1986-05-21 | — | — | EP | disclosed |