Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.68 |
| ▸ | HTR1B | P28222 | 13/20 | 0.68 |
| ▸ | HTR1A | P08908 | 3/20 | 0.68 |
| ▸ | HTR1F | P30939 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9764572 | 0.97 | HTR1D (0.64) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL9764535 | 0.87 | HTR1D (0.64) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL8915046 | 0.86 | HTR1D (0.63) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL27316732 | 0.85 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| Hydrochloric Acid SCHEMBL9269587 | 0.82 | HTR1D (0.57) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL13234805 | 0.82 | HTR1D (0.69) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL20180955 | 0.81 | HTR1D (0.69) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| Naratriptan SCHEMBL29403931 | 0.81 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| Naratriptan SCHEMBL68753 | 0.81 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR1FCYP1A2 | |
| SCHEMBL8786074 | 0.81 | HTR1D (0.63) | HTR1DHTR1BHTR1AHTR1FCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066660-A | INDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-11-19 | — | — | US | disclosed |