Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 6/20 | 0.48 |
| ▸ | CALCR | P30988 | 6/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
| ▸ | NPY4R | P50391 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764520 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL11168683 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL9763775 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL11170810 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL11168724 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL11170849 | 1.00 | RAMP3 (0.48) | RAMP3CALCROPRM1OPRK1MAPK8 | |
| SCHEMBL194515 | 0.95 | OPRM1 (0.48) | RAMP3CALCROPRM1OPRK1 | |
| SCHEMBL1247795 | 0.95 | OPRM1 (0.48) | RAMP3CALCROPRM1OPRK1 | |
| SCHEMBL1247799 | 0.95 | OPRM1 (0.48) | RAMP3CALCROPRM1OPRK1 | |
| SCHEMBL21043608 | 0.95 | OPRM1 (0.48) | RAMP3CALCROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987237-A | Derivatives of monophosphoryl lipid A | RIBI IMMUNOCHEM RESEARCH, INC. (US) | 1991-01-22 | — | — | US | disclosed |
| US-4390528-A | Tuftsinyl-tuftsin | RESEARCH CORPORATION (US) | 1983-06-28 | — | — | US | disclosed |