Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.46 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.46 |
| ▸ | PTPRG | P23470 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459510 | 0.87 | ALDH1A1 (0.64) | KMT2AL3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6937373 | 0.84 | KMT2A (0.70) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL8628655 | 0.83 | POLB (0.65) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL27576529 | 0.81 | KMT2A (0.70) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL7134401 | 0.79 | KMT2A (0.59) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL12024044 | 0.79 | TSHR (0.68) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL6783493 | 0.79 | KMT2A (0.68) | KMT2AL3MBTL1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6289806 | 0.78 | KMT2A (0.70) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL11724672 | 0.78 | KMT2A (0.65) | KMT2AL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL5329475 | 0.78 | TSHR (0.60) | KMT2AL3MBTL1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4995901-A | (Pre- or post-)emergence herbicide; plant growth regulator | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0386001-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4906282-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| WO-1989000991-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-09 | — | — | WO | disclosed |
| EP-0301784-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |