Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | PTPRG | P23470 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831365 | 0.88 | KMT2A (0.56) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL27576529 | 0.87 | KMT2A (0.70) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL9764561 | 0.84 | KMT2A (0.68) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL7136041 | 0.84 | KMT2A (0.58) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL6289806 | 0.83 | KMT2A (0.70) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL292247 | 0.83 | KMT2A (0.61) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL6291181 | 0.83 | KMT2A (0.60) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL11729716 | 0.82 | KMT2A (0.64) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL1901284 | 0.82 | PTPRG (0.67) | KMT2AL3MBTL1MEN1LMNAKDM4E | |
| SCHEMBL14870983 | 0.81 | KMT2A (0.67) | KMT2AL3MBTL1MEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |
| EP-3763704-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2021-01-13 | — | — | EP | disclosed |
| WO-2017191000-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | WO | disclosed |
| EP-0111442-A1 | N-2-heterocyclyl-phenylsulfonyl-N'-pyrimidinyl and like triazinyl urea | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |