SCHEMBL144203

SCHEMBL144203

c1ccc2cc3sccc3cc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.42
CTNNB1 P35222 1/20 0.41
WNT3A P56704 1/20 0.41
CA12 O43570 4/20 0.39
CA2 P00918 4/20 0.39
DYRK1A Q13627 1/20 0.38
PTPRC P08575 1/20 0.38
PTPN6 P29350 1/20 0.38
PTPN11 Q06124 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
RPS6KB2 Q9UBS0 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HBB P68871 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1774665 0.98 CYP2A6 (0.41) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL4585002 0.98 CYP2A6 (0.41) CYP2A6CTNNB1WNT3ACA12CA2
Acetonitrile SCHEMBL28276119 0.88 CYP2A6 (0.37) CYP2A6CTNNB1WNT3ACA12CA2
Benzoquinone SCHEMBL27279715 0.88 CA2 (0.40) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL29733470 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL14041414 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL29733472 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL2344449 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL457633 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2
SCHEMBL2367900 0.87 CYP2A6 (0.46) CYP2A6CTNNB1WNT3ACA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955549-A Method for dehydrogenating and coupling silicon and aromatic heterocyclic compound and application thereof 中山大学 2024-11-15 CN claimed
CN-117343074-A Organic micro-nano eutectic, preparation method thereof and application thereof in near infrared light absorbing material 苏州大学 2024-01-05 CN claimed
CN-110121544-A System and method for being separated from hydrocarbon raw material and extracting heterocyclic compound and polynuclear aromatic hydrocarbons 沙特阿拉伯石油公司 2019-08-13 CN claimed
CN-105873650-B Method for reclaiming organic heteroatomic compound from hydrocarbon feed 沙特阿拉伯石油公司 2018-01-02 CN claimed
CN-106459774-A INTEGRATED SYSTEMS AND METHODS FOR SEPARATION AND EXTRACTION OF POLYNUCLEAR AROMATIC HYDROCARBONS, HETEROCYCLIC COMPOUNDS, AND ORGANOMETALLIC COMPOUNDS FROM HYDROCARBON FEEDSTOCKS 沙特阿拉伯石油公司 2017-02-22 CN claimed
CN-103804659-B A kind of thieno with poly glycol monomethyl ether side chain [3,4-b] thiophene conjugated polymer material, its preparation method and application thereof 中国科学院化学研究所 2016-09-21 CN claimed
CN-105873650-A Methods for recovering organic heteroatom compounds from hydrocarbon feedstocks 沙特阿拉伯石油公司 2016-08-17 CN claimed
CN-103804659-A Thieno [3, 4-b] thiophene conjugated polymer material with polyethylene glycol hematoporphyrin monomethyl ether side chain, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2014-05-21 CN claimed
CN-101253166-B Sulfonamide compound ASAHI KASEI PHARMA CORP 2013-07-10 CN claimed
US-20100209431-A1 METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME NATIONAL UNIVERSITY OF SINGAPORE 2010-08-19 US claimed
US-4293626-A ORGANIC PIGMENT EASTMAN KODAK COMPANY (US) 1981-10-06 US claimed
US-4272595-A UNSATURATED NITRILE EASTMAN KODAK COMPANY (US) 1981-06-09 US claimed
US-4254198-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1981-03-03 US claimed
US-4251609-A Isoquinolinedione photoelectrophoretic materials for imaging processes EASTMAN KODAK COMPANY (US) 1981-02-17 US claimed
US-4241157-A ORGANIC PIGMENTS CONTAINING PYRIMIDINE RING EASTMAN KODAK COMPANY (US) 1980-12-23 US claimed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209431-A1 METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME CASP3, BAX, CASP7 CYP2A6 1359/4885CTNNB1 3469/4885WNT3A 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.