SCHEMBL9764663

SCHEMBL9764663

CCCC[C@H]1CC[C@H](CCc2ccc(CCc3ccccc3)cc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.55
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344771 0.96 HRH3 (0.57) HRH3CARM1PRMT6MAOAMAOB
SCHEMBL9344773 0.96 HRH3 (0.57) HRH3CARM1PRMT6MAOAMAOB
SCHEMBL9156291 0.91 HRH3 (0.52) HRH3CARM1PRMT6MAOAMAOB
SCHEMBL3628266 0.91 HRH3 (0.52) HRH3CARM1PRMT6MAOAMAOB
SCHEMBL8447469 0.87 MAOA (0.54) CARM1PRMT6MAOAMAOB
SCHEMBL11061997 0.87 MAOB (0.54) HRH3MAOAMAOB
SCHEMBL11062001 0.87 MAOB (0.54) HRH3MAOAMAOB
SCHEMBL8447468 0.87 MAOA (0.54) CARM1PRMT6MAOAMAOB
SCHEMBL10788979 0.87 CYP1A2 (0.47) HRH3MAOAMAOB
SCHEMBL10788986 0.87 CYP1A2 (0.47) HRH3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5004324-A Liquid crystal display HOFFMANN-LA ROCHE INC. (US) 1991-04-02 US disclosed