Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250264 | 0.82 | MAOB (0.41) | POLBMAOAMAOBHSD17B10ALDH1A1 | |
| SCHEMBL10394742 | 0.82 | MAOB (0.41) | POLBMAOAMAOBHSD17B10ALDH1A1 | |
| SCHEMBL13525896 | 0.79 | ALDH1A1 (0.41) | KMT2AALDH1A1HPGDEGFRMEN1 | |
| SCHEMBL943161 | 0.78 | APOBEC3G (0.52) | POLBKMT2AALDH1A1HPGDEGFR | |
| SCHEMBL4437147 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1HPGDMEN1MAPK1 | |
| SCHEMBL9507471 | 0.76 | POLB (0.61) | POLBMAOAMAOBHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL4556353 | 0.76 | ALDH1A1 (0.44) | POLBKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL4014797 | 0.76 | MAOA (0.59) | POLBMAOAMAOBHSD17B10KMT2A | |
| SCHEMBL8590717 | 0.76 | CHRNA7 (0.49) | POLBMAOAMAOBKMT2AALDH1A1 | |
| SCHEMBL1902909 | 0.75 | POLB (0.59) | POLBMAOAMAOBHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4995901-A | (Pre- or post-)emergence herbicide; plant growth regulator | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0386001-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4906282-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| WO-1989000991-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-09 | — | — | WO | disclosed |
| EP-0301784-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |