Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764197 | 1.00 | CYP1A2 (0.70) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL27905506 | 1.00 | CYP1A2 (0.70) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL1309620 | 0.87 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL5400012 | 0.87 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL890047 | 0.87 | CYP1A2 (0.67) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL597293 | 0.87 | CYP1A2 (0.63) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL598279 | 0.87 | CYP1A2 (0.63) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL6550685 | 0.86 | CYP2A6 (0.88) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL130783 | 0.85 | CYP1A2 (0.69) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL588278 | 0.84 | CYP1A2 (0.84) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055452-A | Skin disorders | L'OREAL (FR) | 1991-10-08 | — | — | US | disclosed |
| US-4879284-A | SKIN DISORDERS | L'OREAL (FR) | 1989-11-07 | — | — | US | disclosed |
| US-4775663-A | SKIN, EYE DISORDERS; ATROPHY, CARCINOMAS FROM SUNLIGHT | L'OREAL (FR) | 1988-10-04 | — | — | US | disclosed |